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Osteoporosis is a chronic ailment that has rapidly risen to what is considered a severe public health concern in most developed countries. It is a chronic and asymptomatic skeletal disease that requires specialized knowledge along with deft practical nursing skills. It is a course offered to increase the number of physicians who could take care of this growing illness. For this, many aspiring students also reach out for osteoporosis nursing homework help from experts who effectively fuse industry and academia knowledge.
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Osteogenesis And Osteoblasts
The process of bone formation is called osteogenesis. The cells primarily responsible for bone formation and mineralization are called osteoblasts. They develop from mesenchymal stem cells. They are found in clusters lining the bone surface and synthesize collagen that forms the bone matrix and is hardened by mineral deposition, called bone mineralization. There is a significant increase in the osteoblastic activity of these cells when presented with the stimulus of mechanical load or bone fractures. This, in turn, regenerates or reinforces the bone.
Bone Resorption And Osteoclasts
Bone Resorption is an osteological breakdown of the bone material and release of building minerals such as calcium. This forms a vital part of the homeostasis maintained by the body. Osteoclasts are multinucleated cells that are responsible for the process of bone resorption. They are formed from cell division and differentiation of hematopoietic stem cells. The same stem cells also give rise to blood cells by different genetic and biochemical pathways. Osteoclasts are most commonly found in the cavities called Howship’s lacunae of the bone surface. Through there, they carve into the surface of the bone matrix and resorb the bone structure by proteolytic digestion and acidification processes. With the homeostatic activity of osteoblasts and osteoclasts, the bone mass density is maintained in a healthy functioning manner.
Osteoporosis And Its Potential Causes
Osteoporosis may be defined as a chronic skeletal disease. It is marked by a decreased bone mass, which leads to an increase in bone fragility and risk of fracture, especially of the spine, wrist, and pelvic bones, although it could be of any bone. The etymological meaning of the word osteoporosis is “porous or hollow bones” and is amongst the most prevalent bone diseases that exists today. A diminished bone density could result from low levels of calcium or other minerals necessary for bone formation. It is also observed that low levels of estrogen hormone in women are the leading cause of osteoporosis. Sometimes, overactive thyroid, parathyroid, and adrenal glands also become the reason for osteoporosis.
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